… disability. What causes epilepsy? Epilepsy can be caused by changes in the brain from medical conditions such as stroke, multiple sclerosis, traumatic brain injury, … epilepsy due to a family history or because of abnormal structures in their brain from birth. Other times, an individual may develop epilepsy without any known cause. … or while at the movies. If someone becomes unresponsive or has movement changes from a seizure while engaging in activities like biking, cooking or driving, they can …