Ann Seman, MS, CGC is Assistant Professor in the School of Health and Rehabilitation Sciences and Director of Clinical Education for the Master of Science in Genetic Counseling Program at the MGH Institute of Health Professions. As the Director of Clinical Education, Ann teaches Fieldwork I and II, coordinates genetic counseling standardized patient encounters at the IMPACT Practice Center, and coordinates observations and participatory clinical and nonclinical rotations. She enjoys sharing with students how to put together the components of a genetic counseling session, encouraging and witnessing their growth over the course of the program, and welcoming their insights into the counseling process. She feels that learning from the students is just as important as teaching them. Ann also instructs the Embryology and Teratology team-based learning course, where she thrives on the challenge of how to break down and teach the complex concept of the development of each organ system in a way that is relatable to the needs of a genetic counselor. Additionally, Ann participates in the Capstone-related portion of the program by serving on student research committees particularly those focused on pediatrics, laboratory, education, and/or JEDI.

In line with the mission of the IHP, Ann believes in the importance of service and giving back to one's profession. She serves as an Equity Advocate on the School of Nursing Search Committee and is a member of the Program Review Committee for the Accreditation Council for Genetic Counseling. She also is a member of the Philanthropic Education Organization (P.E.O.), which supports women's education through loans, grants, scholarships, awards, and stewardship of Cottey College.

  • MS, Medical Genetics, University of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, OH
  • BS, Molecular, Cellular and Developmental Biology, University of New Hampshire, Durham, NH

Ann has published numerous papers - some titles are highlighted below. You can view a complete listing of Ann's publications in her CV. 

Heterozygous variants in KDM4B lead to global developmental delay and neuroanatomical defects. 

A second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome. 

MN1 C-terminal truncation syndrome is a novel neurodevelopmental and craniofacial disorder with partial rhombencephalosynapsis. 

Novel loss-of-function variants in DIAPH1 are associated with syndromic microcephaly, blindness, and early onset seizures. 

Chromosomal microarray testing for patients with congenital heart defects reveals novel disease-causing loci and high diagnostic yield. 


In addition, Ann regularly presents at conferences and industry events. Please see her CV for a complete list of presentations.

Mosaicism for SRY-Positive Y Chromosome in Karyotype and Chromosomal Microarray Analysis in a Female with Turner syndrome Presentation at the ACMG Annual Clinical Genetics Meeting.

UPD1 in a Child with Multiple Congenital Anomalies at the ASHG Annual Meeting.

FAQ on CMA: Update on Chromosomal Microarray Testing for Neurology at Boston Children’s Hospital.

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